Toxins, Free Full-Text

Staphylococcus aureus is an important pathogen of humans and livestock. It causes a diverse array of diseases, ranging from relatively harmless localized skin infections to life-threatening systemic conditions. Among multiple virulence factors, staphylococci secrete several exotoxins directly associated with particular disease symptoms. These include toxic shock syndrome toxin 1 (TSST-1), enterotoxins, and exfoliative toxins (ETs). The latter are particularly interesting as the sole agents responsible for staphylococcal scalded skin syndrome (SSSS), a disease predominantly affecting infants and characterized by the loss of superficial skin layers, dehydration, and secondary infections. The molecular basis of the clinical symptoms of SSSS is well understood. ETs are serine proteases with high substrate specificity, which selectively recognize and hydrolyze desmosomal proteins in the skin. The fascinating road leading to the discovery of ETs as the agents responsible for SSSS and the characterization of the molecular mechanism of their action, including recent advances in the field, are reviewed in this article.

Toxins, Free Full-Text

Toxics, Free Full-Text, toxicity

Toxins, Free Full-Text, dr neide coutinho

Toxins, Free Full-Text

Toxins, Free Full-Text, duda ferrão games

Why Does a Non-toxic Lifestyle Matter & How do I Get Started?

True Goods ~ Truly Toxin-Free Shopping

Toxins, Free Full-Text

The in vitro effect of lactose on Clostridium perfringens alpha toxin production and the implications of lactose consumption for in vivo anti-alpha toxin antibody production - ScienceDirect

Toxin Free - Carolina Total Wellness

Toxic Nail Polish: More Beauty Industry Lies

Structures of distant diphtheria toxin homologs reveal functional